Naijun Tang,PhD,Professor

Publisher：ggwsxyRelease Time：2019-09-13Browse times：414


Naijun Tang Professor

Department of Occupational and Environmental Health

Email  tangnaijun@


Resume

Research direction

1. Health effects of environmental endocrine disruptors (EDCs) and persistent organic pollutants (POPs).

2. Cohort study on health effects of air pollution.


Education

B.D    Tianjin Medical University, Tianjin, China, 1985

M.D    Tianjin Medical University, Tianjin, China, 1988

Ph.D.   Nankai University, Beijing, China, 2008

Visiting Scholar University of California, Berkeley, USA, 2010


Professional Experience

2018-   Dean, College of Public Health, Tianjin Medical University, Tianjin, China

2012-   Dean, Department of Occupational Health and Environmental Health, Tianjin Medical University, Tianjin, China

2000-   Professor, School of public health, Tianjin Medical University, Tianjin, China

1995-2000 Associate Professor, School of public health, Tianjin Medical University, Tianjin, China

1990-1995 Lecturer, School of public health, Tianjin Medical University, Tianjin, China

1988-1990 Teaching Assistant, School of public health, Tianjin Medical University, Tianjin, China


Project

Ongoing:

1. 2017/07-2020/12, “Research on the cause and control of atmospheric pollution” (2017YFC0211600)- “Early Identification of Respiratory and Cardiovascular Health Effects of Air Pollution” (2017YFC0211605), “13th Five-year” National Key Research and Development Projects, RMB 6730000. (Project leader)

2. 2019/01-2022/12, “Birth cohort study of health effects of air pollution on congenital heart disease” (81872586), National Natural Science Foundation of China，RMB 570000. (Project Leader)

3. 2016/01-2019/12, “Epigenetic Mechanism of ER-positive Breast Cancer Development and Progression of EZH2-mediated Effects of Dioxins” (81573115), National Natural Science Foundation of China，RMB 550000. (Project Leader)

4. 2013/01-2016/12, “Reciprocal Response Mechanism of DEHP and TCDD Co-Exposed to Breast Cancer Development” (81273028), National Natural Science Foundation of China，RMB 700000. (Project Leader)


Completed:


1. 2013/01-2016/12, “Human Exposure Assessment Technology of PCDD/Fs in Typical Industries” (2013090406), The Ministry of Environmental Protection of the People's Republic of China, RMB1060000. (Project leader)

2. 2012/01-2014/12, “The Role of IGF2/H19 in Imprinted Gene IGF2/H19 in Dioxin Transgenerational Genetic Effect and its Molecular Mechanism” (20111202110013), Ministry of Education Doctoral Fund, RMB 120000. (Project leader)

3. 2012/01-2012/12, “ Cross-Generational Genetic Research on Regulation of Steroid Hormone Gene Networks by Intrauterine Dioxin Exposure” (81172629), National Natural Science Foundation of China，RMB 140000. (Project Leader)

4. 2008/04-2011/03, “The research on Risk Factors and Diagnostic Criteria of the Metabolic Syndrome of Public Security Police” (08ZCGYSF01500), Science and Technology Support Program Key Projects, RMB 500000. (Project Leader)


Publication

  1. Shan A#, Li M, Li X, Li Y, Yan M, Xian P, Chang Y, Chen X*, Tang NJ. BDE-47 decreases progesterone levels in BeWo cells by interfering with mitochondrial functions and genes related to cholesterol transport. Chem Res Toxicol. 2019 Feb 4. doi: 10.1021/acs.chemrestox.8b00312. [Epub ahead of print].

  2. Xu H#, Li PH#, Barrow TM, Colicino E, Li C, Song R, Liu H, Tang NJ, Liu S, Guo L*, Byun HM. Obesity as an effect modifier of the association between menstrual abnormalities and hypertension in young adult women: Results from Project ELEFANT. PLoS One. 2018 Nov 28; 13(11):e0207929.

  3. Guo L#*, Peng C#, Xu H#, Wilson A, Li PH, Wang H, Liu H, Shen L, Chen X, Qi X, Tang NJ, Barrow TM, Byun HM. Age at menarche and prevention of hypertension through lifestyle in young Chinese adult women: result from project ELEFANT. BMC Womens Health. 2018 Nov 9; 18(1):182.

  4. Barrow TM#, Peng C, Wilson A, Wang H, Liu H, Shen L, Tang NJ, Sae-Lee C, Li PH, Guo L*, Byun HM. Psychosocial stress is associated with benign breast disease in young Chinese women: results from Project ELEFANT. Breast Cancer Res Treat. 2019 Jan; 173(1):217-224.

  5. Zhang HJ#, Liu YN#, Xian P, Ma J, Sun YW, Chen JS, Chen X*, Tang NJ*. Maternal exposure to TCDD during gestation advanced sensory-motor development, but induced impairments of spatial learning and memory in adult male rat offspring. Chemosphere. 2018 Dec; 212:678-686.

  6. Chen X#, Wang X, Huang JJ, Zhang LW, Song FJ, Mao HJ, Chen KX, Chen J, Liu YM, Jiang GH, Dong GH, Bai ZP*, Tang NJ*. Nonmalignant respiratory mortality and long-term exposure to PM(10) and SO(2): A 12-year cohort study in northern China. Environ Pollut. 2017 Dec; 231(Pt 1):761-767.

  7. Zhang Q#, Yin GY#, Liu J, Liang Y, Li YY, Zhao JY, Zhang LW, Wang BQ, Tang NJ*. Association between MTHFR A1298C polymorphism and male infertility: A meta-analysis. J Huazhong Univ Sci Technolog Med Sci. 2017 Apr; 37(2):153-160.

  8. Li C#,Liu JC#,Xiao X, Chen X,Yue S,Yu H,Tian FS*,Tang NJ*. Psychological distress and type 2 diabetes mellitus: a 4-year policemen cohort study in China. BMJ Open. 2017 Jan 27; 7(1):e014235.

  9. Xi Chen, Xue Wang, Jia-ju Huang, Li-wen Zhang, Feng-ju Song, Hong-jun Mao,Ke-xin Chen, Jie Chen, Ya-min Liu, Guo-hong Jiang, Guang-hui Dong, Zhi-peng Bai, Nai-jun Tang*. Nonmalignant respiratory mortality and long-term exposure to PM10 and SO2: A 12-year cohort study in northern China Environmental Pollution 231 (2017) 761-767

  10. Li C#,Liu JC#,Xiao X, Chen X,Yue S,Yu H,Tian FS*,Tang NJ*. Psychological distress and type 2 diabetes mellitus: a 4-year policemen cohort study in China. BMJ Open. 2017 Jan 27; 7(1):e014235.

  11. Chen X#,Zhang LW#, Huang JJ, Song FJ, Zhang LP, Qian ZM, Trevathan E, Mao HJ, Han B, Vaughn M, Chen KX, Liu YM, Chen J, Zhao BX, Jiang GH, Gu Q, Bai ZP, Dong GH*, Tang NJ*. Long-term exposure to urban air pollution and lung cancer mortality: A 12-year cohort study in Northern China. Sci Total Environ. 2016 Nov 15; 571:855-61.

  12. Li C#, Xing JJ#, Shan AQ, Leng L, Liu JC, Yue S, Yu H, Chen X, Tian FS*, Tang NJ*. Increased risk of nonalcoholic fatty liver disease with occupational stress in Chinese policemen: A 4-year cohort study, Medicine (Baltimore). 2016 Nov; 95(46):e5359.

  13. Leng L#, Li J#, Luo XM, Kim JY, Li YM, Guo XM, Chen X, Yang QY, Li G*, Tang NJ*. Polychlorinated biphenyls and breast cancer: A congener-specific meta-analysis. Environ Int. 2016 Mar; 88:133-41.

  14. Yu H#, Liu JC#, Fan YJ, Li C, Zhang LX, Chen X, Yue S, Lu WL, Yang XL, Tang NJ*. Association between occupational stressors and type 2 diabetes among Chinese police officers: a 4-year follow-up study in Tianjin, China. Int Arch Occup Environ Health. 2016 Feb; 89(2):277-88.

  15. Ma J#, Chen X#, Liu Y, Xie Q, Sun Y, Chen J, Leng L, Yan H, Zhao B*, Tang N*. Ancestral TCDD exposure promotes epigenetic transgenerational inheritance of imprinted gene Igf2: Methylation status and DNMTs. Toxicol Appl Pharmacol. 2015 Dec 1; 289(2):193-202.

  16. Bao J, Zeng XW, Qin XD, Lee YL, Chen X, Jin YH, Tang NJ*, Dong GH*. Phthalate Metabolites in Urine Samples from School Children in Taipei, Taiwan. Arch Environ Contam Toxicol. 2015 Aug; 69(2):202-7.

  17. Chen X, Leng L, Yu H, Yang XL, Dong GH, Yue S, Chen JS, Tang NJ*. Psychological distress and dyslipidemia in chinese police officers: a 4-year follow-up study in Tianjin, China. J Occup Environ Med. 2015 Apr; 57(4):400-5.

  18. Chen X, Chen JS, Zhang L, Li JG, Yao L, Self SG, Sun X*, Tang NJ*. Levels of PCDDs, PCDFs and dl-PCBs in the blood of childbearing-aged women living in the vicinity of a chemical plant in Tianjin: A primary study. Chemosphere. 2015 Jan; 118:1-4.

  19. Zhang LW#, Chen X#, Xue XD, Sun M, Han B, Li CP, Ma J, Yu H, Sun ZR, Zhao LJ, Zhao BX, Liu YM, Chen J, Wang PP, Bai ZP*, Tang NJ*.Long-term exposure to high particulate matter pollution and cardiovascular mortality: A 12-year cohort study in four cities in northern China. Environ Int. 2014 Jan; 62:41-7.

  20. Yu ZR, Ning Y, Yu H, Tang NJ*. A HPLC-Q-TOF-MS-based urinary metabolomic approach to identification of potential biomarkers of metabolic syndrome. J Huazhong Univ Sci Technolog Med Sci. 2014 Apr; 34(2): 276-83.

  21. Leng L#, Chen X#, Li CP, Luo XY, Tang NJ*. 2,3,7,8-Tetrachlorodibezo-p-dioxin exposure and prostate cancer: a meta-analysis of cohort studies. Public Health. 2014 Mar; 128(3): 207-13.

  22. Chen X, Zhou QH, Leng L, Chen X, Sun ZR, Tang NJ*. Effects of Di(n-butyl) and Monobutyl Phthalate on Steroidogenesis Pathways in the Murine Leydig Tumor Cell Line MLTC-1. Environ Toxicol Pharmacol. 2013 Sep; 36(2): 332-8.

  23. Chen X, Liu YN, Zhou QH, Leng L, Chang Y, Tang NJ*. Effects of Low Concentrations of Di-(2-ethylhexyl) and Mono-(2-ethylhexyl) Phthalate on Steroidogenesis Pathways and Apoptosis in the Murine Leydig Tumor Cell Line MLTC-1. Biomed Environ Sci. 2013 Dec; 26(12): 986-9.

  24. Wang Q, Tan HS, Ma XM, Sun Y, Feng NN, Zhou LF, Ye YJ, Zhu YL, Li YL, Brandt-Rauf PW, Tang NJ*, Xia ZL*. Estimation of benchmark dose for micronucleus occurrence in Chinese vinyl chloride-exposed workers. Int J Hyg Environ Health. 2013 Jan; 216(1): 76-81.

  25. Chen X#, Ma SW#, Ma XM, Xu YJ, Tang NJ*. Changes in fibrinopeptide A peptides in the sera of rats chronically exposed to low doses of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Environ Toxicol Pharmacol. 2012 Mar; 33(2): 191-6.

  26. Dong GH, Zhang P, Sun B, Zhang L, Chen X, Ma N, Yu F, Guo H, Huang H, Lee YL, Tang N, Chen J*. Long-term exposure to ambient air pollution and respiratory disease mortality in shenyang, china: a 12-year population-based retrospective cohort study. Respiration. 2012; 84(5): 360-8.

  27. Liu J#, Zhang CM#, Coenraads PJ, Ji ZY, Chen X, Dong L, Ma XM, Han W, Tang NJ*. Abnormal expression of MAPK, EGFR, CK17 and TGk in the skin lesions of chloracne patients exposed to dioxins. Toxicol Lett. 2011 Mar 25; 201(3): 230-4.

Postgraduate training


Recruits students specialized

Preventive medicine


Membership of Academic Society


Committee Member of Academic Society:

The Branch of Environment Health in China Preventive Medicine Association

The Branch of Labor Health and Occupational Diseases in China Preventive Medicine Association

The Branch of Hygiene Toxicology in China Preventive Medicine Association


Membership of Academic Society:

American Toxicology Society

International Commission on Occupational Health


Honors

  1. The Award for Science and Technology Progress in Tianjin (Second Prize), “The Research on the Incidence of Air Pollutants and Multi-organ Disease”(2015jb-2-071-r5), 2015.

  2. Tianjin May 1st Labor Medal, 2009.

  3. The Award for 10th Tianjin Colleges and Universities Teaching Master, 2016.

  4. The Award for Outstanding Teacher of Science and Technology Innovation, 2016.