Yan-Ping Huang, Professor
发布人：药学院-英文  发布时间：2019-12-13   浏览次数:177


Yan-Ping Huang, Ph.D.

 


 


Yan-Ping Huang, PhD

Professor

Department of Pharmaceutical Analysis

School of Pharmacy

Tianjin Medical University

22 Qixiangtai Road

Tianjin 3000070

Phone: +86-15620800828

Email: huangyanping@tmu.edu.cn

 


Education

BD      Beijin Medical University, Beijin, China, 1992

MD     Lanzhou Institute of Chemical Physics, CAS,  China, 1997

Ph.D.  Nankai University, Tianjin, China, 2004

 

Professional Experience

1997.8- up to now     Professor, School of Pharmacy, Tianjin Medical University, Tianjin, China

2009.5-2010.5          Visiting Scholar, School of Pharmacy, UNC-Chapel Hill,  USA

2004.11-2007.3        Post-doctor, Basic medical mobile station,Tianjin Medical University, Tianjin, China

1992.8-1994.7          Research assistant, Lanzhou Institute of Chemical Physics, CAS,  China

 

Honors

1.  Talents in the new century (University level),Tianjin Medical University, Tianjin, China, 2007

2.  1st place, Scientific and Technological Achievements Award, Tianjin Medical University, 2009

3.  Disciplinary Leading Talents in Colleges and Universities in Tianjin，2019

4.  School New Century Talents

5.  Degree Center of the Ministry of Education-Experts in Dissertation Communication Review

6. Director of the Pharmaceutical Quality Analysis and Process Control Branch of China Instrumenta-

tion Society and member of the Pharmaceutical Analysis Branch of Tianjin Pharmaceutical Association

 

Professional Service

 

Reviewer for:

biosensors & bioelectronics

Journal of Chromatography A

Electrophoresis

New Journal Chemistry

Journal of Separation Science

 


Publication

 

  1. Ya-Jie Jiao, Fang-Fang Yuan, Pei-Ru Fan, Ze-Hui Wei, Yan-Ping Huang*,  Zhao-Sheng Liu*, Macroporous monolithic enzyme microreactor based on high internal phase emulsion functionalized with gold nanorods for enzymatic hydrolysis of protein. Chemical Engineering Journal, 2021, 407: 127061.

  2. Zehui Wei，Xue Zhang，Xue Zhao，Ya-Jie Jiao，Yan-Ping Huang*，Zhao-Sheng Liu*. Construction of a microfluidic platform integrating online protein fractionation, denaturation, digestion, and peptide enrichment. Talanta, 2021, 1102:1-10.

  3. Xue Zhang, Jian Yang, Chao Wang, Yakun Sun, Zhaosheng Liu, Yanping Huang*, Haji Akber Aisa*, Improving imprinting effect by reducing sites embedding: Selective extraction of 1,2,3,4,6-penta-o-galloyl-β-d-glucose from paeonia lactiflora pall by hydrophilic molecularly imprinted polymers based on macromonomer and metal ion pivot, Microchemical Journal, 2020,158：105140.

  4. Jian Yang, Xue Zhang, Yasen Mijiti, Yakun Sun, Man Jia, Zhaosheng Liu, Yanping Huang*, Haji Akber Aisa*, Improving performance of molecularly imprinted polymers prepared with template of low purity utilizing the strategy of macromolecular crowding. Journal of Chromatography A, 2020, 1624:461155

  5. Fang-Fang Yuan, Rong-Rong Zhang, Xiaoli Ma, Jian Yang, Yan-Ping Huang*, Zhao-Sheng Liu*, Cooperation effect of 4-vinylbenzeneboronic acid/methacrylic acid on affinity of capecitabine imprinted polymer for drug carrier, European Journal of Pharmaceutical Sciences, 2020,154:105746.

  6. Long Zhao, Mei-Hong Chai, Hong-Fei Yao, Yan-Ping Huang*, Zhao-Sheng Liu*. Molecularly imprinted polymers doped with carbon nanotube with aid of metal-organic gel for drug delivery systems, Pharmaceutical Research, 2020, 37(10):1-14.

  7. Xue Zhang, Yan-Feng Shen, Xin-Xin Li, Jin-Rong Yang, Zhao-Sheng Liu*,Yan-Ping Huang*, Preparation of gold nanorod–incorporated monolith for solid phase extraction of polycyclic aromatic hydrocarbons. Microchimica Acta, 2020, 187(7):418.

  8. Yan-Feng Shen, Xue Zhang, Chun-E Mo, Yan-Ping Huang*, Zhao-Sheng Liu*, Preparation of graphene oxide incorporated monolithic chip based on deep eutectic solvents for solid phase extraction, Analytica Chimica Acta, 2020, 1096, 184-192.

  9. Zehui Wei, Peiru Fan, Yajie Jiao, Yang Wang, Yanping Huang*, Zhaosheng Liu*, Integrated microfluidic chip for on-line proteome analysis with combination of denaturing and rapid digestion of protein. Analytica Chimica Acta, 2020,1102:1-10.

  10. Xue Zhao, Pei-Ru Fan, Chun-E Mo, Yan-Ping Huang*, Zhao-Sheng Liu*, Green synthesis of monolithic enzyme microreactor based on thiol-ene click reaction for enzymatic hydrolysis of protein. Journal of Chromatography A, 2020，1611：460681.

  11. Pei-Ru Fan, Xue Zhao, Ze-Hui Wei, Yan-Ping Huang*, Zhao-Sheng Liu*, Robust immobilized enzyme reactor based on trimethylolpropane trimethacrylate organic monolithic matrix through “thiol-ene” click reaction, European Polymer Journal, 2020, 124, 109456.

  12. Xue Zhang, Mei-Hong Chai, Ze-Hui Wei, Wen-Jing Chen, Zhao-Sheng Liu*, Yan-Ping Huang*, Deep eutectic solvents-based polymer monolith incorporated with titanium dioxide nanotubes for specific recognition of proteins, Analytica Chimica Acta, 2020, 1139:27-35.

  13. Li-Ping Zhang, Ze-Hui Wei, Su-Na He, Yan-Ping Huang, Zhao-Sheng Liu*, Preparation, characterization, and application of soluble liquid crystalline molecularly imprinted polymer in electrochemical sensor. Analytical and Bioanalytical Chemistry, 2020,412:7321-7332.

  14. Long Zhao, Yan-Ping Huang*,Zhao-Sheng Liu*,Xiao-Lin Wang, Li Ma, Ping-Ping Shang,Improving affiffiffinity of β-cyclodextrin-based molecularly imprinted polymer using room temperature ionic liquid. European Polymer Journal,2019,116:275–282.

  15. Jing Feng, Yan-Ping Huang*, Zhao-Sheng Liu*，Fang Li, Rui-Xue Ran, Synergistic effffect of metal ions pivot and macromolecular crowding reagents on affiffiffinity of molecularly imprinted polymer. European Polymer Journal,2019,120,109242.

  16. Chun-E Mo, Yan-Ping Huang*, Zhao-Sheng Liu*，Mei-Hong Chai, Li-Ping Zhang, Rui-Xue Ran, Floating molecularly imprinted polymers based on liquid crystalline and polyhedral oligomeric silsesquioxanes for capecitabine sustained release. International Journal of Pharmaceutics, 2019, 557: 293-303

  17. Ze-Hui Wei, Xuan Sun, Li-Na Mu, Yan-Ping Huang*, Zhao-Sheng Liu*,Improving affifinity of imprinted monolithic polymer prepared in deep eutectic solvent by metallic pivot. Journal of Chromatography A, 2019,1602: 48–55

  18. Wen-Fang Song, Yan-Ping Huang*, Zhao-Sheng Liu*, Qing-Li Zhao, Xiu-Jie Zhou, Li-Shun Zhang,A star-shaped molecularly imprinted polymer derived from polyhedral oligomeric silsesquioxanes with improved site accessibility and capacity for enantiomeric separation via capillary electrochromatography. Microchimica Acta, 2019, 186, 22

  19. Zhang Li-Pin, Huang Yan-Ping*, Liu Zhao-Sheng*, Mo Chun-E, Preparation of Liquid Crystalline Molecularly Imprinted Polymer Coated Metal Organic Framework for Capecitabine Delivery. Particle and Partticle Systems Characterization,2019, 36, 1800355

  20. Yan-Feng Shen, Yan-Ping Huang*, Zhao-Sheng Liu*, Fang-Fang Yuan, Xin-Yu Liu, Synergistic effect of organic-inorganic hybrid monomer and polyhedral oligomeric silsesquioxanes in a boronate affinity monolithic capillary/chip for enrichment of glycoproteins. Microchimica Acta, 2019.

  21. Xue Zhao, Yan-Ping Huang*, Zhao-Sheng Liu*, Green synthesis of monolithic enzyme microreactor based on thiol-ene click reaction for enzymatic hydrolysis of protein. Journal of Chromatography A, 2019.DOI:10.1016/j.eurpolymj.2019.109301

  22. Ze-Hui Wei, Yan-Ping Huang*, Zhao-Sheng Liu*, Fabrication of core-shell sol-gel hybrid molecularly imprinted polymer based on metal–organic framework. European Polymer Journal, 2019. DOI:10.1016/j.chroma.2019.460618

  23. Yi Mu, Xi Wu, Yan-Ping Huang, Zhao-Sheng Liu*, Investigation of deep eutectic solvents as additives to β-CD for enantiomeric separations of Zopiclone, Salbutamol, and Amlodipine by CE. Electrophoresis, 2019, 40: 1992–1995.

  24. Wang Xu, Yang Fang-Fang, Zhang Li-Ping, Huang Yan-Ping*, Liu Zhao-Sheng*, A polyhedral oligomeric silsesquioxane/molecular sieve codoped molecularly imprinted polymer for gastroretentive drug-controlled release in vivo. Biomaterials Science, 2018, 6:3170-3177.

  25. Zhou Xiu-Jie, Huang Yan-Ping*, Liu Zhao-Sheng*, Zhang Li-Shun, Song Wen-Fang, A polymer monolith in corporating stellate mesoporous silica nanospheres for use in capillary electrochromatography and solid phase microextraction of polycyclic aromatic hydrocarbons and organic small molecules. Microchimica Acta, 2018, 185(9): 444-454.

  26. Yang Fang-Fang, Huang Yan-Ping*, Liu Zhao Sheng*, Li Zai-Xuan, Xu Yu-Jing, Enhanced molecular recognition for imprinted monolithic column containing polyhedral oligomeric silsesquioxanes by dendritic effect of mesoporous molecular sieve scaffolds. Analytical and Bioanalytical Chemistry, 2018, 410(21): 5183-5193.

  27. Zhang Li-Ping, Huang Yan-Ping*, Liu Zhao-Sheng*,Tan Xue-Xia, Floating liquid crystalline molecularly imprinted polymer coated carbon nanotubes for levofloxacin delivery. European Journal of Pharmaceutics and Biopharmaceutics, 2018, 127: 150-158.

  28. Zhang Li-Ping, Huang Yan-Ping*, Liu  Zhao-Sheng*,Tang Shi-Hui, Mo Chun-E, Synergistic effect of liquid crystal and polyhedral oligomeric silsesquioxane to prepare molecularly imprinted polymer for paclitaxel delivery. European Polymer Journal, 2018, 98: 226-236.

  29. Li Xin-Xin, Huang Yan-Ping*, Liu Zhao-Sheng*, Zhang Li-Shun, Wang Chao, Green synthesis of monolithic column incorporated with graphene oxide using room temperature ionic liquid and eutectic solvents for capillary electrochromatography. Talanta, 2018, 178: 763-771.

  30. Sun Ya-Kun, Jia Man, Yang Jian, Huang Yan-Ping, Liu Zhao-Sheng, Akber Aisa Haji. A strategy of utilizing Zn（II）as metallic pivot in room temperature ionic liquid to prepare molecularly imprinted polymers for compound with intramolecular hydrogen bonds. Analytical and Bioanalytical Chemistry, 2018, 410(2):349-359.

  31. Zhang Li-Ping, Huang Yan-Ping*, Liu Zhao-Sheng*, Tang Lei, Chen Meng, Wang Xiao-Lin, Qang Qian-Qian,Solvent-responsive floating liquid crystalline-molecularly imprinted polymers for gastroretentive controlled drug release system. International Journal of Pharmaceutics, 2017, 532: 365-373.

  32. Ze-Hui Wei, Yan-Ping Huang*, Zhao-Sheng Liu*, Li-Na Mu, Imprinted monoliths: Recent significant progress in analysis field.Trends in Analytical Chemistry, 2017, 86: 84-92.

  33. Xian-Hua Wang*,Yan-Ping Huang*, Lei Tang, Fang-Fang Yang, Ling-Ling Ying, Zhao-Sheng Liu, Green synthesis of water-compatible and thermo-responsive molecularly imprinted nanoparticles. European Polymer Journal, 2017, 92: 174-184.

  34. Shu-Ping Gao, Yan-Ping Huang*, Zhao-Sheng Liu*, Xue Zhang, Li-Shun Zhang, Molecularly imprinted polymer prepared with polyhedral oligomeric silsesquioxane through reversible addition-fragmentation chain transfer polymerization. Analytical and Bioanalytical Chemistry, 2017, 409 (15): 3741-3748.

  35. Xian-Hua Wang*, Qian Dong, Ling-Ling Ying, Shuai-Shuai Chi, Yao-Han Lan, Yan-Ping Huang, Zhao-Sheng Liu*, Enhancement of selective separation on molecularly imprinted monolith by molecular crowding agent.Analytical and Bioanalytical Chemistry, 2017, 409(1):201-211.




 

Grant

 

Ongoing:

1.National Natural Science Foundation of China, Construction and study of dopant mediated liquid crystal imprinting stationary phase for chiral transfer chromatography (grant No. 21775109), ¥650,000 yuan, 2018.1-2021.12, , project leader

2. Natural Science Foundation of Tianjin city, Study of  imprinting controlled-release contact lens for diabetic retinopathy based on eye-on-a-chip (grant No. 19JCZDJC36400), ¥200,000 yuan, 2019.4-2022.3,  project leader

 

Completed:

  1. National Natural Science Foundation of China, Design, synthesis and chiral drug separation of liquid crystal molecularly imprinted stationary phase based on physical crosslinking (grant No. 21375096), ¥800,000 yuan, 2014.1-2017.12, project leader

  2. The general project of Tianjin Natural Science Foundation Research on the Method of Fluorescence Quantitative PCR Detection of Telomerase Activity (Project No. 08JCYBJC02000), 100,000 yuan. 2008.04-2011.03

  3. Tianjin University Science and Technology Development Fund Development of photosensitizer for introducing peptide nucleic acid into telomerase target (Project No. 20050117), 25,000. 2006.01-2007.12