Cheng-Zhi Xie, Ph.D.
Cheng-Zie Xie, PhD
Associate Professor
School of Pharmacy
Tianjin Medical University
22 Qixiangtai Road
Tianjin 300070
Phone: +86-22-83336658
Email: xiechengzhi@tmu.edu.cn
Education
BD Hebei University, Baoding, China, 1999
MD Nankai University, Tianjin, China, 2002
Ph.D. Tsinghua University, Beijing, China, 2006
Professional Experience
2008-2009 Instructor, School of Pharmacy, Tianjin Medical University, Tianjin, China
2009- Associate Professor, School of Pharmacy, Tianjin Medical University, Tianjin, China
2012-2013 Visiting Scholar, Department of Chemistry, Memphis University, Memphis, USA
Professional Service
Reviewer for:
Dalton Transactions
Journal of Inorganic Biochemistry
New Journal of Chemistry
Spectrochimica Acta Part A
Polyhedron
Applied Organometallic Chemistry
RSC Advances
Photochemical & Photobiological Sciences
Journal of Biomolecular Structure & Dynamics
Inorganic Chemistry Communications
Synthesis and Reactivity in Inorganic, Metal-Organic, and Nano-Metal Chemistry
Publication
1. Xiao-Jing Yan, Zhe Li, Hai-Bo Liu, Zhi-Gang Wang, Jing-Fan, Cheng-Zhi Xie*, Qing-Zhong Li, Jing-Yuan Xu*. A chromone hydrazide Schiff base fluorescence probe with high selectivity and sensitivity for the detection and discrimination of human serum albumin (HSA) and bovine serum albumin (BSA). J. Photoch. Photobio. A, 2022, 422: 113576.
2. Xiao-Jing Yan, Yu-Yang Gao, Hai-Bo Liu, Xin Qiao, Cheng-Zhi Xie*, Qing-Zhong Li, Wei-Zhen Gao, Hua-Bing Sun*, Jing-Yuan Xu*. A novel double target fluorescence probe for Al3+/Mg2+ detection with distinctively different responses and its applications in cell imaging. Spectrochim. Acta A, 2021, 261: 120067.
3. Zhi-Gang Wang, Xiao-Jing Yan, Hai-Bo Liu, De-Long Zhang, Wei Liu, Cheng-Zhi Xie*, Qing-Zhong Li, Jing-Yuan Xu*. A novel hydrazide Schiff base self-assembled nanoprobe for selective detection of human serum albumin and its applications in renal disease surveillance. Journal of Materials Chemistry B, 2020, 8: 8346-8355.
4. Zhi-Gang Wang, Xiao-Jing Ding, Yu-Ying Huang, Xiao-Jing Yan, Bin Ding, Qing-Zhong Li, Cheng-Zhi Xie*, Jing-Yuan Xu*. The development of coumarin Schiff base system applied as highly selective fluorescent/colorimetric probes for Cu2+ and tumor biomarker glutathione detection.Dyes and Pigments, 2020, 175: 108156.
5. Xiao-Jing Yan, Zhi-Gang Wang, Yang Wang, Yu-Ying Huang, Hai-Bo Liu*, Cheng-Zhi Xie*, Qing-Zhong Li, Jing-Yuan Xu*. A dual-functional fluorescent probe for sequential determination of Cu2+/S2− and its applications in biological systems. Spectrochim. Acta A, 2020, 243: 118797.
6. Zhi-Gang Wang, Yang Wang, Xiao-Jing Ding, Yu-Xuan Sun, Hai-Bo Liu, Cheng-Zhi Xie*, Jing Qian, Qing-Zhong Li, Jing-Yuan Xu*. A highly selective colorimetric and fluorescent probe for quantitative detection of Cu2+/Co2+: The unique ON-OFF-ON fluorimetric detection strategy and applications in living cells/zebrafish. Spectrochim. Acta A, 2020, 228: 117763.
7. Xue-Qing Song, Zhi-Gang Wang, Yang Wang, Yu-Ying Huang, Yu-Xuan Sun, Yan Ouyang, Cheng-Zhi Xie*,Jing-Yuan Xu*, Syntheses, characterization, DNA/HSA binding ability, and antitumor activities of a family of isostructural binuclear lanthanide complexes containing hydrazine Schiff base. J. Biomol. Struct. Dyn, 2020, 38: 733-743.
8. Yang Wang, Zhi-Gang Wang, Xue-Qing Song, Qian Chen, He Tian, Cheng-Zhi Xie*, Qing-Zhong Li, Jing-Yuan Xu*, A dual functional turn-on non-toxic chemosensor for highly selective and sensitive visual detection of Mg2+ and Zn2+: the solvent-controlled recognition effect and bio-imaging application. Analyst, 2019, 144: 4024–4032.
9. Yang Wang, Zhong-Ying Ma, De-Long Zhang, Jia-Li Deng, Xiong Chen, Cheng-Zhi Xie* Xin Qiao, Qing-Zhong Li, Jing-Yuan Xu*, Highly selective and sensitive turn-on fluorescent sensor for detection of Al3+ based on quinoline-base Schiff base. Spectrochim. Acta A, 2018, 195: 157–164.
10. Xu-Dong Lin, Biao Peng, Shao-Yong Li, Wei-Guo Bao, Qing-Zhong Li, Cheng-Zhi Xie*, Jing-Yuan Xu*. Novel Zn(II)-thiazolone-based Solid Fluorescent Chemosensors: Naked-eye Detection for Acid/Base and Toluene. RSC Adv., 2016, 6: 52310–52317.
11. Xuan-Wen Liu, Rui Guo, He Liu, Ye-Qi Yu, Xi-Wei Qi, Jing-Yuan Xu, Cheng-Zhi Xie*. Two series of novel 3D potentially porous heterometallic Cu–Ln coordination frameworks assembled by 3,4-pyridinedicarboxylic acid with different topologies and channels: syntheses, structures,
luminescence and magnetic properties. RSC Adv., 2015, 5: 15059-15068.
12. Xiao-Tong Zhang, Zhong-Ying Ma, Chuan Zhao, Qi-Ji Zhou, Cheng-Zhi Xie*, Jing-Yuan Xu*. Synthesis, crystal structures, DNA binding and cytotoxicity activities of two copper(II) complexes based on unsymmetrical tripodal ligands. J. Coord. Chem., 2015, 68: 2307–2323.
13. Ling-Zhi Yuan, Qiang Ge, Xiao-Fei Zhao, Yan Ouyang, Shao-Hua Li, Cheng-Zhi Xie*, Jing-Yuan Xu*. Syntheses, Crystal Structures and DNA Bindings of Co(III) and Ni(II) Complexes Based on 2,6-Bis(benzimidazol-2-yl)-4-hydroxypyridine Ligand. Synth. React. Inorg. Nano-Met. Org. Chem.,2014, 44: 1175-1182.
14. Rui Guo, Xi-Wei Qi, Cheng-Zhi Xie*, Xuan-Wen Liu*, Yue-Hong Zhang, Na Su. Synthesis, Crystal Structure, Magnetic Property and DFT Study of a Novel 2D Polymer [Cu(pdc)(bpy)]•H2O. Chinese J. Struct. Chem., 2014, 33: 270-276.
15. Cheng-Zhi Xie, Meng-Meng Sun, Shao-Hua Li,, Xiao-Tong Zhang, Xin Qiao, Yan Ouyang, Jing-Yuan Xu. Synthesis, characterization, DNA interaction, cytotoxicity, and apoptosis induction of a mixed-ligand copper(II) complex. J. Coord. Chem., 2013, 66: 3891−3905.
16. Fei Xue1, Cheng-Zhi Xie1, Yan-Wen Zhang, Zheng Qiao, Xin Qiao, Jing-Yuan Xu*, Shi-Ping Yan. Two new dicopper(II) complexes with oxamidobridged ligand: Synthesis, crystal structures, DNA binding/cleavage and BSA binding activity. J. Inorg. Biochem., 2012, 115: 78−86.
17. Qiao-Juan Su, Zhong-Ying Ma, Yan Ouyang, Yan-Wen Zhang, Cheng-Zhi Xie*, Jingyuan Xu*. Synthesis, structure, and photoluminescent property of a novel 2D silver(I) polymer based on short Ag-Ag interactions. Synth. React. Inorg. Met.-Org. Chem., 2012,42: 493-497.
18. Ze-Feng Zhang, Zhong-Ying Ma, Dong-Mei Wang, Cheng-Zhi Xie* . A New linear tetranuclear Copper(II) complex: synthesis, structural characterization and magnetic behavior. Synth. React. Inorg. Met.-Org. Chem., 2011, 41: 763-767.
19 Cheng-Zhi Xie, Qiao-Juan Su, Shao-Hua Li, Jing-Yuan Xu, Li-Ya Wang. A novel helical chainlike nickel(II) coordination polymer containing 1D trigonal channels with water molecule guests. Inorg. Chem. Commun. 2010, 13: 1476-1479.
20. Cheng-Zhi Xie, Rong-Fang Li, Li-Ya Wang, Qian-Qian Zhang. Self-assembly and magnetic characterization of two Cu(II) complexes constructed by 2, 2’-bipyridine and 3,5-pyrazoledicarboxylic acid with different structures. Z. Anorg. Allg. Chem. 2010, 636: 657-661.
21. Qi-Ji Zhou, Xue-Jun Yao, Lan-Fang Hao, Yan Ouyang, Jing-Yuan Xu*, Cheng-Zhi Xie*, Jian-Shi Lou. 3,5-Pyrazoledicarboxylic acid with different structures synthesis, crystal structure, and magnetic properties of a new 2D copper(II) polymer constructed by 1,5-dicyanamide and sulfonate anion bridge. Z. Anorg. Allg. Chem. 2010, 636: 2487-2491.
22. Cheng-Zhi Xie, Yan-Zhao Liu, Qiao-Juan Su, Yan Ouyang, Jing-Yuan Xu. A dinuclear nickel(II) complex with dissimilar bridges: synthesis, crystal structure, and magnetic characterization. J. Coord. Chem. 2010, 63: 801-808.
23. Cheng-Zhi Xie, Xin Qiao, Fei Xue, Jing-Yuan Xu. Poly[bis(μ3-5'-carboxy-2,2'-bipyridine-5- carboxylato-κ4O:N,N':O')lead(II)]. Acta Crystallogr. C 2009, 65: 491-493.
24. Cheng-Zhi Xie, Qi-Ji Zhou, Jing-Yuan Xu. A new 3-D Gd(III) coordination polymer constructed with mixed aromatic acid: synthesis, structural characterization and magnetic characterization. J. Chem. Cry. 2009, 39, 799-803.
25. Cheng-Zhi Xie, Bao-Feng Zhang, Xiao-Qing Wang, Bin Yu, Ru-Ji Wang, Guangq-Qiu Shen, De-Zhong Shen. Hydrothermal syntheses, crystal structures and properties of two novel 3-D lanthanide(III) coordination polymers constructed with mixed heterocyclic carboxylic acid. Z. Anorg. Allg. Chem. 2008, 634, 387-391.
26. Cheng-Zhi Xie, Bao-Feng Zhang, Xiao-Qing Wang, Ru-Ji Wang, Guang-Qiu Shen, De-Zhong Shen. The synthesis and structure of a novel alternating 1-D cobalt coordination polymer [Co(2,5-PDC)2(H2O)2Co(H2O)4]4H2O. J. Chem. Cry.,2007, 37, 25-29.
27. Cheng-Zhi Xie, Jian-Hua Qin, Jian-Ge Wang, Chang-Bin Li, Yong-Feng Li,. Diaqua (pyridine-2,4,6-tricarboxylato-kappa N-3,O-2,O-6)- [4-(4-pyridyl) pyridinium-kappa N-1] cobalt(II) dihydrate. Acta Crystallogr. E. 2007, 63: M498-M500.
28. Cheng-Zhi Xie, Ze-Feng Zhang, Bao-Feng Zhang, Xiao-Qing Wang, Ru-Ji Wang, Guang-Qiu Shen, De-Zhong Shen, Bin Ding. A novel 3D CuI metal-organic framework with middle-size channels despite the six-fold ThSi2 interpenetrating topological structure. Eur. J. Inorg. Chem, 2006, 6, 1337-1340.
29. Cheng-Zhi Xie, Bin Yu, Xiao-Qing Wang, Ru-Ji Wang, Guang-Qiu Shen, De-Zhong Shen. Syntheses and structures of M-Na (M = Zn, Mn) coordination polymers in which ligands and Na ions exhibit complex coordination modes. J. Coord. Chem. 2006, 59, 2005-2014.
30. Cheng-Zhi Xie,, Bao-Feng Zhang, Xuan-Wen Liu, Xiao-Qing Wang, Hui-Zhong Kou, Guang-Qiu Shen, De-Zhong Shen. Synthesis, crystal structure, and magnetic property of a novel 2D polymer [Co(PDC(4,4-bpy)](CH3OH). Inorg. Chem. Commun. 2004, 7, 1037-1040.
31. Cheng-Zhi Xie, Ze-Feng Zhang, Xiao-Qing Wang, Xuan-Wen Liu, Guang-Qiu Shen, Ru-Ji Wang, De-Zhong Shen. The synthesis and structure of a novel 1D copper(II) weak coordination polymer with 2,6-pyridinedicarboxylic acid. J. Coord. Chem. 2004, 57, 1173-1178.
32. Cheng-Zhi Xie, Bao-Feng Zhang, Xiao-Qing Wang, Guang-Qiu Shen, De-Zhong Shen. Catena-poly[[[tetraaquacobalt(II)]-mu-4,4-bipyridine-kappa N-2:N '] phthalate dihydrate]. Acta Crystallogr. E. 2004, 60: M1703-M1705.
33. Cheng-Zhi Xie, Shi-Ping Yan,Chun-Hui Li, Peng Cheng, Dai-Zheng Liao, Zong-Hui Jiang. Synthesis, structure and properties of {Cu2(tacn)2[μ-(MeN)2C2O2][(MeNH)2C2O2](ClO4)2. Acta. Chim. Sinica 2002, 60, 293-297.
Grant
Ongoing:
Syntheses of small molecules with natural product skeleton, Cooperative project, 2019.11-2022.11
Synthesis of slignans, Cooperative project, 2020.10-2023.10
Completed:
Tianjin Municipal Natural Science Foundation (No. 18JCYBJC91300), Design, syntheses and biological imaging of novel fluorescent probes for tracing the metabolism of thiolcontaining small molecules, 2018.10-2021.09.
Opening fund for the Key Laboratory of Advanced Energy Materials Chemistry (Ministry of Education), Design, synthesis and properties of novel zinc ion fluorescent probe based on Schiff base, 2016.1-2018.12.
Study on the synthesis technology of magnetic beads for effective nucleic acid extraction, Cooperative project, 2017.11-2020.11
Chinese Postdoctoral Science Foundation, Antitumor and against drug resistance activities Study of nitrogen-containing heterocyclic platinum complexes with thiourea group, Grant No. 2014M551036,2014.2-2015.6.
