Sheng-an Tang, Ph.D.
Shengan Tang, PhD
Associate Professor
School of Pharmacy
Tianjin Medical University
22 Qixiangtai Road
Tianjin 300070
Phone: +86-22-83336679
Email: tangshengan@tmu.edu.cn
Education
Ph.D. Shenyang Pharmaceutical University, Shenyang, China, 2005
B.Eng. Shenyang Pharmaceutical University, Shenyang, China, 2001
Professional Experience
2008- Associate Professor, School of Pharmacy, Tianjin Medical University, Tianjin, China
Research Interests
We hope to find bioactive lead compounds from concise traditional Chinese herbal medicine by using new bioactive screening technology, efficient and convenient separation and purification methods.
1)Discovery and mechanism of anti rheumatoid arthritis active components in natural products;
2)Rapid discovery of enzyme inhibitors in traditional Chinese Medicine;
3)Establishment and application of rapid screening method for bioactive components from concise traditional Chinese herbal medicine
Books
Modern Principles ＆ Clinic on Chinese Materia Medica (Chinese), Editorial Board, 2012, Tianjin Science & Technology Translation & Publishing Corp.
Publication
1. Wei-Guo Xu, Jiao-Jiao Xu, Jia Wang, Guo-Sheng Xing, Wei Qiao, Hong-Quan Duan, Chuan Zhao*, Sheng-An Tang*, Axinellin A and B: Two New Pyrrolactam Alkaloids from Axinella sp., Chemistry of Natural Compounds, 2017, 53(2), 325-327.
2. Jia Wang, Pei Su, Qiong Gu, Wei Dong Li, Jia Lin Guo, Wei Qiao,; Dan Qing Feng*, Sheng An Tang*, Antifouling activity against bryozoan and barnacle by cembrane diterpenes from the soft coral Sinularia flexibilis, International Biodeterioration & Biodegradation, 2017, 120, 97-103
3. Chuan Zhao, Jia Wang, De-Jun Jin, D Hong-Quan uan, Guo-Sheng Xing*, Sheng-AnTang*, Two new eunicellin diterpenoids from the East China Sea gorgonian Muricella sp., J Asian Nat Prod Res, 2016, 18(9), 848-853
4. Wei-Guo Xu, Jia Wang, Guo-Sheng Xing, Jiao-Jiao Xu, Wei Qiao, Chuan Zhao*, Sheng-An Tang*, Jaspiferin G, a new isomalabaricane-type triterpenoid from the sponge Jaspis stellifera, Z Naturforsch C, 2016, 71(5-6), 111-114
5. Chuan Zhao, Guo-Sheng Xing, Rong Xu, De-Jun Jin, Hong-Quan Duan, Wei-Guo Xu*, Sheng-An Tang*, Rabdosia Acids A and B: Two New Lipids from Rabdosia lophanthoides, Chemistry of Natural Compounds, 2016, 52(2), 205-207
6. Yang Jiao, Jing-Bo Fang, Sheng-An Tang*, Hong-QuanDuan*, Penangianol A and B: Two New Norlignans from Rhizomes of Abacopteris penangiana, Chemistry of Natural Compounds, 2015,51(2), 232-235
7. Chuan Zhao, Qiong Gu, Wei-Guo Xu, Guo-Sheng Xing, DE-Jun Jin, Rong Xu, He Li, Hong-Quan Duan, Jin Zhou*, Sheng-An Tang*, Three new polyunsaturated lipids from a Guangxi marine sponge Haliclona sp., Journal of Asian Natural Products Research, 2015, 17(2), 114-119
8. Wen Chen, Xiao-Ai Shou, Ying Chen, Nan Qin, Wei Qiao, Sheng-An Tang*, Hong-Quan Duan*, A New Aurone from Smilax riparia, Chemistry of Natural Compounds, 2014,50(6), 989-993
9. Sheng-An Tang, Qianxiang Zhou, Wen-Zhi Guo, Yuling Qiu, Ran Wang, Meihua Jin, Wenjing Zhang, Ke Li, Takao Yamori, Shingo Dan, and Dexin Kong. In Vitro Antitumor Activity of Stellettin B, a Triterpene from Marine Sponge Jaspis stellifera, on Human Glioblastoma Cancer SF295 Cells. Marine Drugs. 2014, 12, 4200-4213.
10.Sheng-An Tang, Hong Zhu, Nan Qin, Jing-Ya Zhou, Eunkyung Lee, De-Xin Kong, Mei-Hua Jin, Hong-Quan Duan. Anti-inflammatory Terpenes from Flowers of Inula japonica. Planta Medica. 2014, 80 (7), 583-589.
11. De-Jun Jin, Sheng-An Tang*, Guo-Sheng Xing, Wen-Jun Zhao, Chuan Zhao, Hong-Quan Duan, Wen-Han Lin*. Jaspiferins C–F, four new isomalabaricane-type triterpenoids from the South China Sea sponge Jaspis stellifera. Journal of Asian Natural Products Research. 2014, 16 (5), 427-433.
12. Rong Xu, Mei-Hua Jin, Yang Jiao, Guo-Sheng Xing, Chuan Zhao, Hong-Quan Duan*, Sheng-An Tang*. Novel polyhydroxylated steroids from the East China Sea gorgonian Echinogorgia sassapo reticulata with suppressive activity of leukotriene C4 generation and degranulation in bone marrow-derived mast cells. Journal of Asian Natural Products Research. 2014, 16 (4), 351-357.
13. Sheng-An Tang, Lin-Lin Ding, Hui-Yuan Zhai, Nan Qin and Hong-Quan Duan. Four new triterpenes from the endemic relict shrub Tetraena mongolica. Journal of Asian Natural Products Research. 2012, 14 (9), 838-843.
14. Tang, Shengan*, Xu, Rong, Lin, Wenhan, Duan, Hongquan, Jaspiferin A and B: Two New Secondary Metabolites from the South China Sea Sponge Jaspis stellifera. Records of Natural Products, 2012, 6 (4), 398-401.
15. Shengan Tang, Zhiwei Deng, Peter Proksch, Wenhan Lin, Jaspolides G and H, unique bisisomalabaricanes from the Chinese marine sponge jaspis sp., Tetrahedron Letters, 2007, 48, 5443-5447
16. Shengan Tang, Yue Hu Pei, Hong Zheng Fu, Zhi Wei Deng, Wen Han Lin, Jaspolide A-F, six new isomalabricane-type terpenoids from the sponge Jaspis sp., Chemical & Pharmaceutical Bulletin，2006，54(1) 4-8
17. Shengan Tang, Zhi Wei Deng, Hong Zheng Fu, Yue Hu Pei, Si Zhang, Wen Han Lin, A New Isomalabaricane Triterpenoid from Sponge Jaspis sp., Chinese chemical letters, 2005, 16, 353-355.
Grant
Ongoing:
1. the Key Program of National Natural Science Foundation of Tianjin under Grant 16JCZDJC32600;
2. the China Postdoctoral Science Foundation under Grant 2016M591399;
Completed:
1. the National Natural Science Foundation of China 81102371;
2. the Natural Science Foundation of Tianjin under Grant 10JCYBJC15000.
