WeiLi Dong, Ph.D.
WeiLi Dong, PhD
Associate Professor
School of Pharmacy
Tianjin Medical University
22 Qixiangtai Road
Tianjin 30000780
Phone: +86-22-83336659
Email: dongweili@tmu.edu.cn
Education
BD Xinyang Normal University, Xinyang, China, 2003
MD Nankai University, Tianjin, China, 2006
Ph.D. Nankai University, Tianjin, China, 2009
Professional Experience
2009-2012 Instructor, Department of Pharmacy, Tianjin Medical University, Tianjin, China
2012- Associate Professor, Department of of Pharmacy, Tianjin Medical University, Tianjin, China
Honors
1.Tianjin 12th college young teachers teaching basic skills competition (The third prize) in 2014.
2. National college pharmacy professional young teachers micro class teaching competition (The second prize) in 2019.
Reviewer for:
Bioorganic &Medicinal Chemistry
Bioorganic &Medicinal Chemistry Letters
Chemical Biology & Drug Design
European Journal of Medicinal Chemistry
Phosphorus, Sulfur, and Silicon and the Related Elements
Publication
(1) Xin-Bang Peng#; Di He#; Guan-Nan Sun; Yu Yu; Ying-Hong Ma; Sheng-An Tang*; Wei-Li Dong*; Shao-Yong Li*; Mononitration of a Calix[4]arene Methylene Bridge: Synthesis and Preliminary Catalysis Performances of Bridging Chiral p-tert- Butylcalix[4]arenes with a Monoamino Bridge Substituent in a 1,3-Alternate Conformation, The Journal of Organic Chemistry, 2021, 86(5):3952-3959.
(2) Xiu-Jiang Du; Xing-Jie Peng; Rui-Qi Zhao; Wei-Guang Zhao*; Wei-Li Dong*;Xing-Hai Liu*; Design, synthesis and antifungal activity of threoninamide carbamate derivatives via pharmacophore model, Journal of Enzyme Inhibition and Medicinal Chemistry, 2020, 35(1): 682-691.
(3) Hao Ma#; Xiu-Fang Weng#; Shan-Shan Ren; Zi-Ying Tang; Xin-Bang Peng; Yong He; Shuang Zheng*; Wei-Li Dong*; Shao-Yong Li*; Synthesis of Bridging Chiral p–tert-Butylcalix[4]arenes with One and Two Carbamoyl Bridge-Substituents through Anionic Ortho-Fries Rearrangement, ChemistrySelect, 2020, 5(21): 6274-6277.
(4) Wen-Shan Liu, Rui-Rui Wang, Hai Yue, Zhi-Hui Zheng, Xin-Hua Lu,Shu-Qing Wang, Wei-Li Dong* & Run-Ling Wang*, Design, synthesis, biological evaluation and molecular dynamics studies of 4-thiazolinone derivatives as protein tyrosine phosphatase 1B (PTP1B) inhibitors. Journal of Biomolecular Structure and Dynamics, 2019, 38(13):3814-3824.
(5) Hong- Lian Li, Ying Ma, Ying Ma, Yu Li, Xiu-Bo Chen, Wei-Li Dong*, Run-Ling Wang*, The design of novel inhibitors for treating cancer by targeting CDC25B through disruption of CDC25B-CDK2/Cyclin A interaction using computational approaches. Oncotarget, 2017, 8(20): 33225-33240.
(6) Yong Zhu, Wen Zhao, Liang Han, Wei-Li Dong*, Xing-Hai Liu*, Synthesis and Insecticidal, Anticancer Activity of Novel Pyrazole Acyl Urea Derivatives. J.Chem.Soc.Pak., 2017, 39(3): 464-470
(7) Wei-Li Dong, Wen-Xi Cai, Zheng-Ming Li, Wei-Guang Zhao, A convenient method for reduction dehalogenation of α- halocarbonyl compounds using benzenethiol in K+/CH3CN system. Phosphorus, Sulfur, And Silicon, 2016, 191(7): 980-983.
(8) Wen-Xi Cai, Ai-Lin Liu, Zheng-Ming Li, Wei-Li Dong*, Xing-Hai Liu*. Synthesis and Anticancer Activity of Novel Thiazole-5-Carboxamide Derivatives. Appl. Sci. 2016, 6, 8.
(9) Wei-Li Dong, Jun-Ying Xu , Li-Xia Xiong, Zheng- Ming Li, Synthesis, structure and insecticidal activity of some novel amides containing N-pyridylpyrazole, J Iran Chem Soc, 2013, 10:429–437.
(10) Wei-Li Dong, Jing-Ying Xu, Li-Xia Xiong, Zheng-Ming Li, Synthesis, Structure and Insecticidal Activities of Some Novel Amides Containing N-Pyridylpyrazole Moeities, Molecules, 2012, 17, 10414-10428.
(11) Wei-Li Dong, Zheng-Xiao Liu, Xing-Hai Liu, Zheng-Ming Li, Wei Guang Zhao, Synthesis and Antiviral Activity of New Acrylamide Derivatives containing 1,2,3-thiadiazole as Inhibitors of Hepatitis B Virus Replication. European Journal of Medicinal Chemistry, 2010, 45, 1919-1926.
(12) Zhi-Rong Deng, Shu-Qing Wang, Wei-Li Dong*, Ethyl 4-[(4-chlorophenoxy)methyl]-2-(4-nitrophenyl)-1,3-thiazole-5-carboxylate, Acta Cryst. 2011, E67, o3433.
Grant
Ongoing:
(1)Natural Science Foundation of Tianjin (NO: 18JCYBJC89800):Design, synthesis and bioactivity of new amino-acid amide derivatives as cellulose synthase inhibitors (2018.04-2022.03),Project leader.
Completed:
(1) National Natural Science Foundation of China (NO:21102103):Design, Synthesis and Antiviral Activity of New Acrylamide Derivatives containing Heterocycle (2012.01-2014.12), Project leader.
(2) China Postdoctoral Science Foundation (NO:2011M500532): Design, Synthesis and Antiviral Activity of Novel Acrylamide Derivatives containing Thiadiazole (2011.03-2013.03), Project leader.
(3) China Postdoctoral Science Foundation funded project (NO:2014T70222): Study on multicomponent reactions in the synthesis of heterocyclic amides and anti-HBV activity (2014.07-2018.07), Project leader.
