Xiaoying Yang, PhD
Xiaoying Yang, PhD
Professor
School of Pharmacy
Tianjin Medical University
22 Qixiangtai Road
Tianjin 300070
Phone: +86-22-83336658
Email: yangxiaoying@tmu.edu.cn
Education
B.S. Nankai University, Tianjin, China, 1992
M.S. Nankai University, Tianjin, China, 2002
Ph.D. Nankai University, Tianjin, China, 2006
Postdoctoral Fellow Tianjin Medical University, Tianjin, China, 2012
Professional Experience
2013- Professor, School of Pharmacy, Tianjin Medical University, Tianjin, China
2008-2013 Associate Professor, School of Pharmacy, Tianjin Medical University, Tianjin, China
1992-2008 Instructor, School of Pharmacy, Tianjin Medical University, Tianjin, China
Honors
1. Eleven Five New Century Talents of Tianjin Medical University
Professional Service
Reviewer for:
ACS Nano
ACS Applied Materials & Interfaces
Chemical Communications
ACS Applied NANO Materials
Journal of Materials Chemistry B
Nanoscale
Journal of Controlled Release
Expert Opinion in Drug Delivery
New Journal of Chemistry
Polymer Chemistry
Current Drug Delivery
Langmuir
Current Medicinal Chemistry
RSC Advances
Materials Research Bulletin
Publication
1）Zhaoyang Guo, Liting Wu, Yang Wang, Yanpeng Zhu, Guoyun Wan, Rongshan Li, Yinghua Zhang, Dong Qian, Yinsong Wang*, Xiang Zhou*, Zunfeng Liu, Xiaoying Yang*. Design of dendritic large-pore mesoporous silica nanoparticles with controlled structure and formation mechanism in dual-templating strategy. ACS Applied Materials & Interfaces, 2020, 12, 18823−18832.
2）Chunhui Gao, Yinghua Zhang, Yan Zhang, Shaoyong Li, Xinlin Yang, Yan Chen, Jingwei Fu, Yinsong Wang*, Xiaoying Yang*. cRGD-modified and disulfide bond-crosslinked polymer nanoparticles based on iopamidol as a tumor-targeted CT contrast agent.Polymer Chemistry, 2020, 11(4), 889-899.
3）YajunJiang, ZhaoyangGuo, JingFang, BeibeiWang, Zhiqiang Lin, Zhe-Sheng Chen, Yan Chen, Ning Zhang, Xiaoying Yang*,WeiGao*. A multi-functionalized nanocomposite constructed by gold nanorod core with triple-layer coating to combat multidrug resistant colorectal cancer.Materials Science and Engineering: C, 2020,107, 110224.
4）Beibei Wang, Sunyi Wu, Zhiqiang Lin, Yajun Jiang, Yan Chen, Zhe-Sheng Chen, Xiaoying Yang*, Wei Gao*. A personalized and long-acting local therapeutic platform combining photothermal therapy and chemotherapy for the treatment of multidrug-resistant colon tumor. International Journal of Nanomedicine, 2018, 13, 8411-8427.
5）Qianyu Zhang, Li Wang, Yajun Jiang, Wei Gao, Yinsong Wang, Xiaoying Yang*, Xinlin Yang, Zunfeng Liu*. Gold nanorods with silica shell and PAMAM dendrimers for efficient photothermal therapy and low toxic codelivery of anticancer drug and siRNA. Advanced Materials Interfaces,2017, 4(24), 1701166 (1-9).
6）Xinghua Liu, Chunhui Gao, Junheng Gu, Yunfang Jiang, Xinlin Yang, Shaoyong Li, Wei Gao, Tong An, Hongquan Duan, Jingwei Fu, Yinsong Wang*, Xiaoying Yang*. Hyaluronic acid stabilized iodine-containing nanoparticles with Au nanoshell coating for X-ray CT imaging and photothermal therapy of tumors. ACS Applied Materials & Interfaces, 2016, 8(41), 27622-27631.
7) Yunfang Jiang, Qianyu Zhang, Xinghua Liu, Yifu Chen, Li Wang, Jingwei Fu, Hongquan Duan, Yinsong Wang, Xiaoying Yang*. Au nanoshell-coated superparamagnetic Fe3O4–silica composite nanoparticles with surface modification of an activatable cell-penetrating peptide for tumor-targeted multimode bioimaging and photothermal therapy. RSC advances,2016, 6(88), 85587-85594.
8) Yunfang Jiang, Xinghua Liu, Jing Li, Lei Zhou, Xiaoying Yang*, Yi Huang*. Enhanced electrochemical oxidation of p-nitrophenol using single-walled carbon nanotubes/silver nanowires hybrids modified electrodes. Journal of Nanoscience and Nanotechnology,2015, 15, 6078-6081.
9) Xiufen Cao, Shuang Zheng, Sipei Zhang, Yinsong Wang, Xiaoying Yang*, Hongquan Duan, Yi Huang*, and Yongsheng Chen. Functionalized graphene oxide with hepatocyte targeting as anti-tumor drug and gene intracellular transporters. Journal of Nanoscience and Nanotechnology, 2015, 15, 2052-2059.
10) Fuli Feng, Rongrong Li, Qingyun Zhang, Yinsong Wang, Xiaoying Yang*, Hongquan Duan, Xinlin Yang*. Preparation of reduction-triggered degradable microcapsules for intracellular delivery of anti-cancer drug and gene. Polymer, 2014, 55, 110-118.
11）Rongrong Li, Fuli Feng, Yinsong Wang, Xiaoying Yang*, Xinlin Yang*, Victor C. Yang. Folic acid-conjugated pH/temperature/redox multi-stimuli responsive polymer microspheres for delivery of anti-cancer drug. Journal of Colloid and Interface Science, 2014, 429, 34-44.
12）Xiufen Cao, Fuli, Feng, Yinsong Wang, Xiaoying Yang*, Hongquan Duan, Yongsheng Chen. Folic acid-conjugated graphene oxide as a transporter of chemotherapeutic drug and siRNA for reversal of cancer drug resistance. Journal of Nanoparticle Research, 2013, 15, 1965-1976.
13）Xiaoying Yang,* Gaoli Niu, Xiufen Cao, Yuku Wen, Rong Xiang,* Hongquan Duan and Yongsheng Chen*. The preparation of functionalized graphene oxide for targeted intracellular delivery of siRNA. Journal of Materials Chemistry,2012, 22, 6649-6654.
14）Xiaoying Yang*, Yinsong Wang, Xin Huang, Yanfeng Ma, Yi Huang, Rongcun Yang, Hongquan Duan and Yongsheng Chen*. Multi-functionalized graphene oxide based anticancer drug-carrier with dual-targeting function and pH-sensitivity. Journal of Materials Chemistry,2011, 21, 3448-3454.
15）Xiaoying Yang*, Lei Chen, Bin Han, Xinlin Yang*, Hongquan Duan. Preparation of magnetite and tumor dual-targeting hollow polymer microspheres with pH-sensitivity for anticancer drug-carriers. Polymer,2010, 51, 2533-2539.
16）Xiaoying Yang*, Xiaoyan Zhang, Yanfeng Ma, Yi Huang, Yinsong Wang, Yongsheng Chen*, Superparamagnetic graphene oxide–Fe3O4 nanoparticles hybrid for controlled targeted drug carriers. Journal of Materials Chemistry,2009,19, 2710–2714.
17）Xiaoying Yang*, Liting Chen, Bo Huang, Feng Bai, Xinlin Yang*. Synthesis of pH-Sensitive Hollow Polymer Microspheres and Their Application as Drug Carriers”. Polymer, 2009,50, 3556–3563.
18）Xiaoying Yang*, Xiaoyan Zhang, Zunfeng Liu, Yanfeng Ma, Yi Huang,Yongsheng Chen*, High-efficiency loading and controlled release of doxorubicin hydrochloride on graphene oxide. Journal of Physical Chemistry C2008, 112, 17554–17558.
19）Xiaoying Yang*, Zhuohan Zhang, Zunfeng Liu, Yanfeng Ma, Rongcun Yang, Yongsheng Chen*. Multi-functionalized single-walled carbon nanotubes as tumor cell targeting biological transporters. Journal of Nanopartcle Research, 2008, 10, 815–822.
Grant
Ongoing:
The National Natural Science Foundation of China (No. 12074284): Study on a multi-functional nanosystem for synergistic anti-tumor treatment using low dose X-ray and near-infrared light. (2021.01-2024.12), Project leader.
The Natural Science Foundation of Tianjin City (No. 20JCYBJC00170):Construction and application of biomimetic system based on dendritic large-pore mesoporous silica with high oxygen carrying for tumor combination treatment of radiotherapy, radiodynamic and photothermal therapy. (2020.04-2023.03), Project leader.
Completed:
1. The Applied Basic and Frontier Technology Research Program of Tianjin City (No. 15JCZDJC36300): Study on CT contrast agent mediated by activatable cell penetrating peptides for tumor targeted imaging (2015.04-2018.03), Project leader.
2. Young Science Foundation of the National Natural Science Foundation of China (No. 51103106): Studies forhepatic targeted siRNA and anticancer drugs co-delivery system based on grapheme oxide. (2012.01-2014.12), Project leader.
3. Young Science Foundation of the National Natural Science Foundation of China (No. 51103106): Studies forhepatic targeted siRNA and anticancer drugs co-delivery system based on grapheme oxide. (2012.01-2014.12), Project leader.
4. China Postdoctoral Science Foundation (No. 20100480042): The preparation of multi-functional graphene oxide based targeted gene carriers. (2010.12-2012.12), Project leader.
5. The Applied Basic and Frontier Technology Research Program of Tianjin City（No. 07JCYBJC01700）：Studies for single-walled carbon nanotube based hepatic targeted anti-cancer drug delivery systems (2007.04-2009.09), Project leader.
6. Horizontal Project: Preparation technology of carbon nanotubes and biological composite sensors (2012.11-2014.10). Project leader.
