Yuguang Song, Ph.D.
Yuguang Song, PhD
Associate Professor
School of Pharmacy
Tianjin Medical University
No.22 Qixiangtai Road
Heping District, Tianjin, 300070 China
Phone: 86-022-83336658 (O)
Email: songyuguang@
Website: /s/9/t/814/4e/01/info19969.htm
Education
B.S. Heilongjiang University, Heilongjiang, China, 1995-1999
M.S. Northeast Agricultural University, Heilongjiang, China, 1999-2002
Ph.D. Institute of Chemistry, Chinese Academy of Sciences, Beijing, China, 2004-2007
Postdoctoral Researcher The Ohio State University, Ohio, USA, 2010-2013
Professional Experience
2002-2004 Assistant Professor, Institute of Chemistry, Chinese Academy of Sciences, Beijing, China
2013- Associate Professor, Department of Medicinal Chemistry, Tianjin Medical University, Tianjin, China
Honors
1. Excellent Leadership, Heilongjiang University, 1998
2. Excellent Students Scholarship, Heilongjiang University, 1999
3. Excellent Students Scholarship, Northeast Agricultural University, 2002
Professional Service
Committee member of Youth Committee, Chinese Society of Free Radical Biology and Medicine
Committee member of Youth Committee, Research Association of Modern Medical Care
Editorial Board
Reviewer for:
Membership of Academic Society
Biophysical Society of China
Chinese Society of Chemistry
Publications
1. Xiaoli Tan, Li Chen, Yuguang Song*, Antal Rockenbauer, Frederick A. Villamena, Jay L. Zweier, and Yangping Liu*, Thiol-dependent reduction of the triester and triamide derivatives of Finland trityl radical triggers O2-dependent superoxide production, Chem. Res. Toxicol. 2017, 30 (9), 1664–1672.
2. Pengjiao An，Nannan Yu，Ruisheng Sun，Xiaofang Sui*, Yuguang Song*, Characterization of the interaction between an esterified TAM radical with bovine serum albumin, Chem. J. Chinese Universities，2017, 38(8):1354-1361.
3. Wenbo Liu, Jiangping Nie, Xiaoli Tan, Huiqiang Liu, Nannan Yu, Guifang Han, Yutian Zhu, Frederick A. Villamena, Yuguang Song, Jay L. Zweier*, and Yangping Liu*. Synthesis and Characterization of PEGylated Trityl Radicals: Effect of PEGylation on Physicochemical Properties. J. Org. Chem. 2017, 82, 588-596
4. Xiaoli Tan, Yuguang Song,* Huiqiang Liu,a Qinwen Zhong,* Antal Rockenbauer, Frederick A. Villamena, Jay L. Zweier and Yangping Liu,* Supramolecular host–guest interaction of tritylnitroxide biradicals with cyclodextrins: modulation of spin–spin interaction and redox sensitivity, Org. Biomol. Chem., 2016, 14(5): 694-1701 （IF=3.562）
5. Yuguang Song, Yangping Liu, Wenbo Liu, Frederick A. Villamena, and Jay L. Zweier, Characterization of the binding of the Finland trityl radical with bovine serum albumin, RSC Adv., 2014, 4, 47649-47656
6. Yuguang Song, Yangping Liu, Craig Hemann, Frederick A. Villamena, and Jay L. Zweier, Esterified dendritic TAM radicals with very high stability and enhanced oxygen sensitivity, J. Org. Chem., 2013, 78 (4): 1371-1376.
7. Yangping Liu, Frederick A. Villamena, Antal Rockenbauer, Yuguang Song, and Jay L. Zweier, Structural factors controlling the spin-spin exchange coupling: EPR spectroscopic studies of strongly asymmetric trityl-nitroxide biradicals, J Am Chem Soc., 2013, 135 (6): 2350-2356.
8. Yangping Liu1, Yuguang Song1, Francesco De Pascali, Xiaoping Liu, Frederick A.Villamena, Jay L. Zweier, Tetrathiatriarylmethyl radical with a single aromatic hydrogen as a highly sensitive and specific superoxide probe, Free Radical Biol. Med., 2012, 53: 2081-2091.
9. Yu-guang Song, Bin Liu, Yangping Liu, Frederick A.Villamena and Yang Liu, Biphasic regulation of Superoxide radical levels in Mn-depleted and photoactivated PSII, Photosynthetica, 2011, 49 (3): 353-360.
10. Yangping Liu1, Yuguang Song1, Li-bo Du, Frederick A. Villamena, Yiqiong Ji, Qiu Tian, Ke-Jian Liu, and Yang Liu, Novel Glutathione-linked Nitrones as Dual Free Radical Probes, New J. Chem., 2011, 35: 1485-1490.
11. Yangping Liu, Yuguang Song, Antal Rockenbauer, Jian Sun, Craig Hemann, Frederick A. Villamena, and Jay L. Zweier, Synthesis of trityl-conjugated disulfide biradicals for the measurement of thiol concentration, J. Org. Chem., 2011, 76: 3853-3860.
Grant
Ongoing:
1. Natural Science Foundation of China, The molecular design, synthesis and characterization of superoxide spin trap based on trityl radicals, 01/2016—12/2019, PI, ￥239,200
2. Natural Science Foundation of Tianjin, The design and characterization of EPR/Fluorescence two-mode superoxide probe, 04/2015—03/2018, PI, ￥100,000
