Meihua Jin, Ph.D.
Tianjin Meihua Jin, PhD
Associate Professor
Department of Pharmacy
Tianjin Medical University
22 Qixiangtai Road
Tianjin 30000780
Phone: +86-13370369063
Email: jinmeihua@tmu.edu.cn
Education
MD Yeungnam University, Gyeongsan, Gyeongbuk, Korea, 2003
Ph.D. Yeungnam University, Gyeongsan, Gyeongbuk, Korea, 2005
Postdoctoral Fellow Tianjin Medical University, Tianjin, China, 2016
Professional Experience
2011- Associate Professor, Department of Pharmacy, Tianjin Medical University, Tianjin, China
2009-2011 Assistant Professor, Department of Pharmacy, Yeungnam University, Gyeongsan, Gyeongbuk, Korea
Honors
1. The second class candidate of Tianjin “131” innovative talent training project in 2012
2. Excellent young teachers program of Tianjin, 2012.
Professional Service
Membership of Academic Society
Chinese pharmaceutical society (CNPHARS)
Publication
1. X Chen, N Ji, N Qin, SA Tang, R Wang, Y Qiu, H Duan, D Kong, M Jin*. 1,6-O,O-Diacetylbritannilactone Inhibits Eotaxin-1 and ALOX15 Expression Through Inactivation of STAT6 in A549 Cells. Inflammation 2017; 40(6):1967-1974. (Correspondence author)
2. Y Chen, N Ji, S Pan, Z Zhang, R Wang, Y Qiu, M Jin*, D Kong*. Roburic Acid Suppresses NO and IL-6 Production via Targeting NF-kappaB and MAPK Pathway in RAW264.7 Cells. Inflammation 2017; 40(6):1959-1966. (Correspondence author)
3. M Jin*, S Kim, N Qin, X Chen, N Ji, SA Tang, D Kong, E Lee, H Duan. 1,6-O,O-Diacetylbritannilactone suppresses activation of mast cell and airway hyper-responsiveness. Immunopharmacol Immunotoxicol 2017; 39(4): 173-179. (First and Correspondence author)
4. X Wei, Y Chen, H Zhu, X Wu, Y Yu, D Kong, H Duan *, M Jin*, N Qin*. Synthesis and anti-inflammatory activities of 1-O-acetylbritannilactone analogues. Phytochem Lett 2017; 19: 248-253. (Correspondence author)
5. X Chen, SA Tang, E Lee, Y Qiu, R Wang, HQ Duan, S Dan, M Jin*, D Kong*. IVSE, isolated from Inula japonica,suppresses LPS-induced NO production via NF-kappaB and MAPK inactivation in RAW264.7 cells. Life Sci 2015; 124: 8-15. (Correspondence author)
6. X Wang, SA Tang, R Wang, Y Qiu, M Jin*, D Kong*. Inhibitory Effects of JEUD-38, a New Sesquiterpene Lactone from Inula japonica Thunb, on LPS-Induced iNOS Expression in RAW264.7 Cells. Inflammation 2015; 38(3): 941-948. (Correspondence author)
7. M Jin, Q Zhou, E Lee, S Dan, HQ Duan, D Kong*. AS252424, a PI3Kgamma inhibitor, downregulates inflammatory responsiveness in mouse bone marrow-derived mast cells. Inflammation 2014; 37(4): 1254-1260.
8. S Tang, H Zhu, N Qin, J Zhou, E Lee, D Kong, M Jin*, HQ Duan*. Anti-inflammatory terpenes from flowers of Inula japonica. Planta Med 2014; 80(7): 583-589. (Correspondence author)
9. M Jin, W Zhao, Y Zhang, M Kobayashi, H Duan*, D Kong*. Antiproliferative effect of aaptamine on human chronic myeloid leukemia K562 cells. Int J Mol Sci 2011; 12(11): 7352-7359.
10. M Jin, Y Lu, J Yang, T Jo, Y Park, C Lee, S Park, K Son*, H Chang*. Anti-inflammatory activity of 6-hydroxy-2,7-dimethoxy-1,4-henanthraquinone from tuberous roots of yam (Dioscorea batatas) through inhibition of prostaglandin D(2) and leukotriene C(4) production in mouse bone marrow-derived mast cells. Arch Pharm Res 2011; 34(9): 1495-1501.
11. M Jin, K Son*, H Chang*. Luteolin-7-O-glucoside suppresses leukotriene C(4) production and degranulation by inhibiting the phosphorylation of mitogen activated protein kinases and phospholipase Cgamma1 in activated mouse bone marrow-derived mast cells. Biol Pharm Bull 2011; 34(7): 1032-1036.
12. Y Lu, M Jin, S Park, K Son, J Son *, H Chang *. Batatasin I, a naturally occurring phenanthrene derivative, isolated from tuberous roots of Dioscorea batatas suppresses eicosanoids generation and degranulation in bone marrow derived-mast cells. Biol Pharm Bull 2011; 34(7): 1021-1025. (Co-first author)
Grant
Ongoing:
1. National Natural Science Foundation of China, The mechanism study of growth inhibition of breast cancer through IgE receptor FcεRI-activated mast cell (81672809), 2017.01-2020.12.
2. China Postdoctoral Science Foundation Funded Project, The anti-inflammatory effect and mechanism study of boruric acid (2016M601277), 2016.11-2018.10.
Completed:
1. National Natural Science Foundation of China, Study on the anti-asthmatic multi molecular mechanisms by using lactone probe from Inula japonica and discovery of lead compound (81202542), 2013.01-2015.12.
2. Natural Science Foundation of Tianjin, Using ABLOO as a probe to study its anti-asthmatic multi molecular mechanisms and their synergistic effects (13JCYBJC24800), 2013.04-2016.03.
3. New Teachers’ Fund for Doctor Stations from Ministry of Education, China (20121202120009), 2013.01.01-2015.12.31.
4. Project Sponsored by the Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry, 2013.09-2016.08.
