吴晓辉教授 博士生导师
发布时间: 2022-02-24 浏览次数: 1162

姓名

吴晓辉

职称

教授,博士生导师

所在部门

药学院

 研究方向

临床药理学,中药现代化

办公室

药学院B302

办公电话

022- 

83336659

电子邮箱

xiaohuiwu@

教育背景

1999  9 —2003  6 月:华中科技大学同济医学院,药学,理学学士

2005  9 —2010  6 月:华中科技大学同济医学院,药理学,医学博士

2007  9 —2010  5 月:中国科学院上海药物所,药理学,联合培养博士

工作经历

2021  1 至今:全球正规十大网赌,药学院,教授

2013  1 —2020  12 月:全球正规十大网赌,药学院,副教授

2013  8 —2014  8 月:美国芝加哥大学,公派访问学者

2010  7 —2012  12 月:全球正规十大网赌,药学院,讲师

2003  7 —2005  6 月:武汉市第四医院,临床药师

研究成果(本人近三年的代表性通讯作者论文,及主持的科研项目

论文

(1) Dan WangLi TianChang ShiYuXi WeiHan WangTianTian LiuMing GongYanWen ZhangRongGuo YuXiaoHui Wu*. Network pharmacology-based prediction of the active ingredients and mechanism of Shen Gui capsule for application to coronary heart disease. Comput Biol Med. 2020; 122: 103825. (JCR 一区)

(2) Lijun An, Jun Ma, Xueyuan Yang, Yue Liang, Huimei Wang, Muhetaer Tuerhong, Namrita Lall, Munira Abudukeremu, Yi Zhang, Dongho Lee, Jing Xu, Xiaohui Wu*, Yuanqiang Guo*. Caseahomopene A, a Ring-Expanded Homotriterpenoid From Casearia Kurzii Showing Anti-Inflammatory Activities in Vitro and in Vivo. Bioorganic Chemistry. 98 (2020) 103758. (JCR 一区)

(3) Huiping Li, Yeqing Gu, Xiaohui Wu*, Sabina Rayamajhi, Shanshan Bian, Qing Zhang, Ge Meng, Li Liu, Hongmei Wu, Shunming Zhang, Yawen Wang, Tingjing Zhang, Xuena Wang, Amrish Thapa, Shaomei Sun, Xing Wang, Qiyu Jia, Kun Song, Kaijun Niu*. Association between consumption of edible seaweeds and newly diagnosed non-alcohol fatty liver disease: the TCLSIH Cohort Study. Liver Int. 2021; 41(2): 311-320. (JCR 一区)

(4) Shunming Zhang, Shubham Kumari, Yeqing Gu, Xiaohui Wu*, Xiaoyue Li, Ge Meng, Qing Zhang, Li Liu, Hongmei Wu, Yawen Wang, Tingjing Zhang, Xuena Wang, Xingqi Cao, Huiping Li, Yunyun Liu, Xiaohe Wang, Shaomei Sun, Xing Wang, Ming Zhou, Qiyu Jia, Kun Song, Zhong Sun, Kaijun Niu*. Soy Food Intake Is Inversely Associated with Newly Diagnosed Nonalcoholic Fatty Liver Disease in the TCLSIH Cohort Study. J Nutr. 2020 Oct 23; doi: 10.1093/jn/nxaa297. (JCR 一区)

(5)Yeqing Gu, Ge Meng, Qing Zhang, Li Liu, Hongmei Wu, Shunming Zhang, Yawen Wang, Tingjing Zhang, Xuena Wang, Shaomei Sun, Xing Wang, Ming Zhou, Qiyu Jia, Kun Song, Xiaohui Wu*, Kaijun Niu. Predictive Value of Thyroid Hormones for Incident Hyperuricemia in Euthyroid Subjects: The Tianjin Chronic Low-Grade Systemic Inflammation and Health Cohort Study. Endocrine Practice. 2021, 27(4): 291-297. (JCR )

(6) Dan WangChang ShiZhen-Hua GeYu-Xi WeiTian-Tian LiuYue WangXin-Feng ZhouZi-Jun YangWei-Ting WangYan-Wen ZhangXue-Hui ZhuJun ZhangYing LiMin GongXiao-Hui Wu*Hong-Quan Duan. Study of the Mechanism of Action of Guanxin Shutong Capsules in the Treatment of Coronary Heart Disease Based on Metabolomics. Front Pharmacol. 2021; 12: 650438. (JCR 一区)

(7) Dan WangJialin GuoTiantian LiuXinfeng ZhouZijun YangChang ShiWeiting WangRongshan LiYanwen ZhangJun zhangJiuxing YanXuehui ZhuYing LiMin GongYan CuiXiaohui Wu*. Plasma metabolomics-based reveals the treatment mechanism of ShenGui capsule for application to coronary heart disease in a rat model. Anal Biochem. 2022; 642: 114480. (JCR )

(8) Zijun YangDan WangYuanyuan LiXinfeng ZhouTiantian LiuChang ShiRongshan LiYanwen ZhangJun ZhangJiuxing YanXuehui ZhuYing LiMin GongChongzhi WangChunsu YuanYan CuiXiaohui Wu*. Untargeted metabolomics analysis of the anti-diabetic effect of Red ginseng extract in Type 2 diabetes Mellitus rats based on UHPLC-MS/MS. Biomed Pharmacother. 2022; 146: 112495. (JCR 一区)

(9) Tiantian LiuDan WangXinfeng ZhouJiayin SongZijun YangChang ShiRongshan LiYanwen ZhangJun ZhangJiuxing YanXuehui ZhuYing LiMin GongChongzhi WangChunsu YuanYan CuiXiaohui Wu. Study on the mechanism of American ginseng extract for treating type 2 diabetes mellitus based on metabolomics. Front Pharmacol. 2022;13: 960050. (JCR 一区)

科研项目

(1) 国家自然科学基金,基于 URAT1 靶点的牛尾菜总皂苷抗高尿酸血症活性成分及及作用机制研究,No. 812028952013.01-2015.12,主持

(2) 国家自然科学基金,牛尾菜调控 NLRP3/Caspase-1/PDZK1 轴抗高尿酸血症的药效物质及作用机制研究,No. 819745212020.01-2023.12,主持

(3) 天津市自然科学基金重点项目,牛尾菜总皂苷协同别飘呤醇抗高尿酸血症活性成分及协同机制研究,No. 19JCZDJC335002019.04-2022.03,主持

(4) 教育部留学回国人员科研启动基金,鸡血莲抗前列腺增生活性成分及作用机制研究,2015.08-2017.08,主持

(5) 中国博士后基金面上项目,基于网络药理学探索牛尾菜总皂苷多成分多靶点抗高尿酸血症的整合作用机制,No. 2013M5308822013.06-2015.06,主持

(6) 中国博士后特别资助基金,基于网络多靶点的鸡血莲抗前列腺增生活性成分研究,No. 2014T702232014.06-2016.06,主持

(7) 天津市自然科学基金重点项目,靶向抑制 PIK3 对前列腺癌转移的影响及机理研究,No. 12JCZDJC258002012.4-2015.3


荣誉奖励

天津市高校中青年骨干创新人才

全球正规十大网赌卓越教师

其他事项

世界中医药联合会中药分析专业委员会理事

天津市药理学会理事

天津市中药传承创新发展专家委员会委员

天津市围手术期医学研究会理事

天津市药理学会实验药理学专业委员会副主任委员

天津市药理学会网络药理学专业委员会副主任委员

天津市药理学会定量药理学专业委员会副主任委员

国家自然科学基金、科技部科技项目、教育部硕博士学位论文等的评审专家

牛津大学高级研究学者