马菲 教授
流行病与卫生统计学系
电子邮件 mafei@
简历
马菲,博士,全球正规十大网赌教授,博士生导师,天津市131第二层次人才,主要研究方向是“营养与神经科学”。近年来以项目负责人承担国家自然科学基金面上项目2项,国家自然科学基金国际(地区)合作项目1项,国家自然科学基金青年项目1项;以第二、第五负责人参研国家自然科学基金重点项目2项,以第二负责人参研天津市科技支撑重点项目1项。近年来以第一作者和通讯作者在European journal of neurology、J Neurol Neurosurg Psychiatry、J Gerontol A Biol Sci Med Sci.、European journal of nutrition、Journal of Alzheimer's Disease等国际学术刊物发表SCI论文17篇,总影响因子累计80.729,引用次数360次。
研究方向
近年来的主要研究方向是:营养流行病学
学习经历
1. 2006~2009年,山西医科大学预防医学系,博士学位
2. 2002~2005年,第三军医大学预防医学系,硕士学位
3. 1995~2000年,第三军医大学预防医学系,学士学位
工作经历
1. 2009年至今,全球正规十大网赌公共卫生学院流行病与卫生统计学系,讲师,副教授,教授
2. 2005~2006年,沈阳军区联勤部疾病预防控制中心,疾病控制科医师
3. 2000~2002年,沈阳军区联勤部疾病预防控制中心,疾病控制科医师
主要承担或参与的课题
1. 性别/社会经济地位在体力活动与轻度认知障碍向痴呆转变关系中的修饰作用,国家自然科学基金国际合作项目,82111530242,3万元,2021 09-2023.02。
2. 基于端粒-端粒酶系统维生素D3对轻度认知功能障碍改善作用机制的研究,国家自然科学基金面上项目,81874261,57万元,2018.01-2021.12。
3.基于端粒叶酸对神经细胞凋亡及延缓老年人认知减退的作用及机制研究,国家自然科学基金重点项目,81730091,300万元,2019.01-2022.12。
4.基于LncRNA调控Aβ诱导自噬探讨维生素D3对阿尔茨海默病作用机制,国家自然科学基金面上项目,81573148,57万元,2016.01-2019.12。
5. DHA及其代谢物对社区轻度认知功能障碍老年人群干预研究,中国营养学会营养科研基金--帝斯曼专项科研基金,2014-003,14.8万元,2014.06- 2016.06。
6.社区老年人2型糖尿病伴轻度认知功能障碍发生现状及转归研究,国家自然基金青年基金,81001282,20万元,2011-2013。
7.淀粉样前蛋白基因对轻度认知功能障碍老年人不同认知能区损伤作用效果,全球正规十大网赌科学基金,2009ky09,1万元,2010.01-2010.12。
8.以社区为基础叶酸、维生素B12联合防治阿尔茨海默病干预技术研究,天津市科技支撑重点项目,15ZCZDSY01040,30万元,2015.10-2018.09。
9.叶酸和DHA联合应用对轻度认知功能障碍老年人干预作用的研究,汤臣倍健营养科学研究基金项目,TY0151102,35万元,2016.01-2019.06。
10.大豆蛋白对无症状高尿酸血症代谢作用机制的研究,国家自然基金青年基金,81302422,23万元,2014-2016。
11.基于DNA甲基化途径叶酸对阿尔茨海默病作用机制,国家自然基金重点项目,81130053,260万元,2012-2016。
发表论著(标注#为第一作者,标注*为通讯作者)
[1] Xiaomin Wu#,Hualou Wang,Chong Chen,Ying Xiong,Liping Zhu,Jingya Jia,Tong Yang,Fei Ma*. The association between cardiovascular risk burden and cognitive function among the old: a 9-year longitudinal cohort study[J]. European journal of neurology. 2021.28.(9):2907-2921.(JCR一区,IF: 6.089,5-years IF: 5.308)
[2]Yang T#, Wang H, Xiong Y, Chen C, Duan K, Jia J, Ma F*. Vitamin D supplementation improves cognitive function through reducing oxidative stress regulated by telomere length in older adults with mild cognitive impairment: a 12-month randomized controlled trial[J]. J Alzheimers Dis. 2020;78(4):1509-1518. (JCR二区,IF: 3.909,5-years IF: 4.023)
[3]Fei Ma#, Xuan Zhou#, Qing Li, Jiangang Zhao, Aili Song, Peilin An, Yue Du,Weili Xu, Guowei Huang*. Effects of folic acid and vitamin B12, Alone and in combination on cognitive function and inflammatory factors in the elderly with mild cognitive impairment: a single-blind experimental design[J]. Current Alzheimer Research.2019; 16(7), 622-632. (JCR二区,IF: 3.271,5-years IF: 3.309)
[4]Fei Ma#,Xin Lv#,Yue Du, Hui Chen,Shuai Liu,Jiangang Zhao,Yiming Gao,Peilin An, Xuan Zhou,Aili Song,Changqing Sun,Guangshun Wang,Yong Ji,Xinyan Wang, Weili Xu, Guowei Huang*. Association of leukocyte Ttelomere length with mild cognitive impairment and Alzheimer's disease: role of Ffolate and homocysteine. Dement Geriatr Cogn Disord. 2019;48(1-2):56-67. (JCR二区,IF: 2.260,5-years IF: 3.157)
[5] Fei Ma#, Qing Li, Xuan Zhou, Jiangang Zhao, Aili Song, Wen Li, Guowei Huang*. Effects of folic acid supplementationon cognitive function and Aβ-related biomarkers in mild cognitive impairment: arandomized controlled trail. European journal of nutrition. 2019, 58(1): 345-356. (JCR一区,IF: 5.719,5-years IF: 6.352)
[6]Jia J#, Hu J, Huo X, Miao R, Zhang Y, Ma F*. Effcets of vitamin D supplementation on cognitive function and blood Aβ-related biomarkers in older adults with Alzheimer’s Disease: a randomized, double-blind, placebo-controlled trial. J Neurol Neurosurg Psychiatry 2018, 89(12): 1341-1347. (JCR一区,IF: 8.327,5-years IF: 7.383)
[7]Hu J#, Jia J, Zhang Y, Miao R, Huo X, Ma F*. Effects of vitamin D3 supplementation on cognition and blood lipids:a 12-month randomised,double-blind,placebo-controlled trial.J Neurol Neurosurg Psychiatry.2018 Oct 2.pii:jnnp-2018-318594. (JCR一区,IF: 7.144,5-years IF: 6.923)
[8]Zhang Y P#, Lou Y, Hu J, Miao R, Ma F*. DHA supplementation improves cognitive function via enhancing Aβ-mediated autophagy in Chinese elderly with mild cognitive impairment: a randomised placebo-controlled trial. J Neurol Neurosurg Psychiatry. 2018, 89(4): 382-388 (JCR一区,IF: 7.144,5-years IF: 6.923)
[9]Fei Ma#, Tianfeng Wu Jiangang Zhao, Lu Ji, Aili Song, Meilin Zhang,Guowei Huang*. Plasma homocysteine and serum folate and vitamin B12 levels in mild cognitive impairment and alzheimer’s disease: a case-control study. Nutrients. 2017, 9(7), 725. (JCR一区,IF: 3.550,5-years IF: 4.187)
[10]Yanping Zhang#, Rujuan Miao, Qing Li, Tianfeng Wu,Fei Ma*. Effects of DHA supplementation on hippocampal volume and cognitive function in older adults with mild cognitive impairment: a 12-month randomized, double-blind, placebo-controlled trial. Journal of Alzheimer's Disease. 2017; 55(2): 497-507. (JCR二区,IF: 3.920,5-years IF: 3.804)
[11] Fei Ma#, Tianfeng Wu, Jiangang Zhao, Aili Song, Huan Liu,Weili Xu,Guowei Huang*. Folic acid supplementation improves cognitive function via lowering the levels of peripheral inflammatory cytokines in Chinese elderly with MCI.Scientific Reports. 2016; 6: 37486. (JCR二区,IF: 5.228,5-years IF: 4.857)
[12] Fei Ma#, Tianfeng Wu, Jiangang Zhao, Fengmei Han, Anna Marseglia, Huan Liu, Guowei Huang*. Effects of six-month folic acid supplementation on cognitive function and blood biomarkers in Mild Cognitive Impairment: a randomized controlled trial in China. Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences. 2016 Oct;71(10):1376-1383. (JCR一区,IF: 5.476,5-years IF: 5.783)
[13] Fei Ma#, Tianfeng Wu, Jiangang Zhao, Lu Ji, Aili Song, Meilin Zhang,Guowei Huang*. Prevalence of mild cognitive impairment and is subtypes among Chinese older adults:role of vascular factors. Dementia and Geriatric Cognitive Disorders. Dement Geriatr Cogn Disord. 2016; 41: 261-272. (JCR二区,IF: 3.228,5-years IF: 3.707)
[14] Qian He#, Qing Li, Jiangang Zhao, Tianfeng Wu, Lu Ji, Guowei Huang, Fei Ma*. Relationship between plasma lipids and mild cognitive impairment in the elderly Chinese: a case-control study. Lipids Health Dis. 2016 Sep 5, 15:146. (JCR二区,IF: 2.137,5-years IF:2.531)
[15] Yuxia Gao#, Yanyu Xiao, Rujuan Miao, Jiangang Zhao, Mingfei Cui,Guowei Huang, Fei Ma*. The prevalence of mild cognitive impairment with type 2 diabetes mellitus among elderly people in China: a cross-sectional study. Arch Gerontol Geriatr. 2016 Jan-Feb;62:138-42. (JCR二区,IF: 1.858,5-years IF: 2.155)
[16] Fei Ma#, Tianfeng Wu, Rujuan Miao, Yanyu Xiao, Wenwen Zhang, Guowei Huang*. Conversion of mild cognitive impairment to dementia among subjects with diabetes: a population-based study of incidence and risk factors with five years of follow-up. J Alzheimers Dis. 2015,43(4):1441-1449. (JCR二区,IF: 3.612,5-years IF: 4.365)
[17] Yuxia Gao#, Yanyu Xiao, Rujuan Miao, Jiangang Zhao, Wenwen Zhang,Guowei Huang, Fei Ma*. The characteristic of cognitive function in Type 2 diabetes mellitus. Diabetes Research and Clinical Practice. Diabetes Res Clin Pract. 2015 Aug;109(2):299-305. (JCR三区,IF: 3.074,5-years IF: 3.308)
研究生培养情况
硕士生在读6名,在职2名,毕业2名
招生专业
流行病与卫生统计学、公共卫生
社会兼职
中华预防医学会慢病分会 委员
天津市心脏学会流行病分会 常务委员兼秘书长
天津市预防医学会流行病分会 委员
中西医结合学会循证医学分会 青年委员
获奖情况
2017.6 中国营养学会颁发“全国营养行业先进工作者”称号
2014.6 2014年度天津市“131”创新型人才培养工程第二层次人才
2014.3 天津市高校优秀青年教师资助计划